Infantile myofibromatosis is an uncommon, benign, self-limiting, localized or generalized process, probably of hamartomatous origin, which consists to a large degree of cells having the characteristics of myofibroblasts and sometimes of
pericytes.
Both
solitary and multicentric forms occur. Most lesions are present at birth or in early infancy, and some are familial in origin.
A female newborn presented with a firm, round, red colored, 3×3 cm sized tumor with central necrosis on the left chest. Histological examination revealed well-circumscribed nodules consisting of short bundles of plump, spindle shaped cells
displaying
staining characteristics intermediate between fibroblasts and smooth muscle cells. The tumor was immunoreactive for actin but did not stain for desmin. A Follow-up examination at the age of 3 moderate degree of spontaneous regression of the
lesion.
(Kor
J Dermatol 1997;35(1) : 182∼186)
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